CUSIP 91678A107COMUPBQ4 2025
12 filings · latest Nov 14, 2025
Largest reported positions · latest quarter
| # | Fund | Shares | Value |
|---|---|---|---|
| 1 | Fmr LLC | 7.52M | $204.12M |
| 2 | Orbimed Advisors LLC | 5.69M | $154.58M |
| 3 | Blackrock, Inc. | 3.34M | $90.80M |
| 4 | Decheng Capital LLC | 3.14M | $85.33M |
| 5 | Norges Bank | 2.88M | $78.26M |
| 6 | Enavate Sciences Gp, LLC | 2.46M | $66.78M |
| 7 | Vanguard Group Inc | 2.39M | $64.85M |
| 8 | Ubs Group AG | 1.81M | $49.04M |
| 9 | Janus Henderson Group PLC |
| 4 | Aug 6, 2025 | Fmr LLC | 13G/A | 14.8% | 7.94M | SEC |
| 5 | Feb 14, 2025 | Decheng Capital Global Life Sciences Fund IV, L.P. | 13G | 6.1% | 3.29M | SEC |
| 6 | Feb 14, 2025 | Tcg Crossover Gp I, LLC | 13G | 11.0% | 2.80M | SEC |
| 7 | Feb 13, 2025 | Hbm Healthcare Investments (Cayman) Ltd. | 13G | 5.1% | 2.72M | SEC |
| 8 | Feb 12, 2025 | Fmr LLC | 13G/A | 13.4% | 7.18M | SEC |
| 9 | Nov 7, 2024 | Fmr LLC | 13G | 11.8% | — | SEC |
| 10 | Oct 22, 2024 | Ai Upstream LLC | 13D | 10.7% | 5.49M | SEC |
See the full Schedule 13D/13G history for Upstream Bio Inc.
Unlock full history| 1.53M |
| $41.42M |
| 10 | Altshuler Shaham Ltd | 1.34M | $36.42M |