Institutional Ownership
Spero Therapeutics Inc
CUSIP 84833T103COMSPROQ1 2026
Institutional Holders
47
13F filers
Shares Held
18.55M
Aggregate institutional
Institutional Value
$42.75M
Q1 2026
Net New Holders
-6
5 new · 11 closed
Institutional Ownership Trend
Aggregate 13F value by quarter
Multi-quarter trend — upgrade to see history
UpgradePosition Activity
Q1 2026
New positions5
Increased12
Decreased11
Sold out11
Institutional Holders
47 funds hold this security · Q1 2026
| # | Fund | Shares | Value | Δ Shares | Activity |
|---|---|---|---|---|---|
| 1 | Gsk PLC | 9.19M | $21.51M | 0 | Held |
| 2 | Pfizer Inc | 2.36M | $5.50M | 0 | Held |
| 3 | Renaissance Technologies LLC | 1.19M | $2.78M | −90.3K | Reduced |
| 4 | Alphabet Inc. | 890.0K | $2.08M | 0 | Held |
| 5 | Two Sigma Investments, LP | 885.6K | $2.07M | +513.1K | Added |
| 6 | Geode Capital Management, LLC | 519.9K | $1.22M | −9.3K | Reduced |
| 7 | Blackrock, Inc. | 433.2K | $1.01M | −414 | Reduced |
| 8 | Anson Funds Management LP | 422.0K | $987.4K | −203.1K | Reduced |
| 9 | Citadel Advisors LLC | 376.5K | $880.9K | −21.4K | Reduced |
| 10 | Susquehanna International Group, LLP | 333.1K | $779.5K | +39.4K | Added |
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