Institutional Ownership
Prelude Therapeutics Inc
CUSIP 74065P101COMPRLDQ1 2026
13D / 13G Filings
27
Schedule 13D/13G on record
Beneficial Filers
9
Distinct reporting persons
Largest Stake
33.9%
Max % of class reported
Institutional Holders
52
13F filers (latest quarter)
Beneficial Owners — Schedule 13D / 13G
27 filings · latest Feb 13, 2026
| # | Filed | Reporting Person | Form | % of Class | Shares | Filing |
|---|---|---|---|---|---|---|
| 1 | Feb 13, 2026 | Vaddi Krishna | 13G/A | 13.2% | 6.75M | SEC |
| 2 | Nov 7, 2025 | Incyte Corp | 13G | 9.9% | 4.37M | SEC |
| 3 | Jun 13, 2025 | Baker Bros. Advisors LP | 13D/A | 23.5% | — | SEC |
| 4 | May 15, 2025 | Vaddi Krishna | 13G/A | 13.8% | 6.40M | SEC |
| 5 | Feb 14, 2025 | Vaddi Krishna | 13G/A | 11.0% | 5.49M | SEC |
| 6 | Feb 13, 2025 | Deerfield Mgmt, L.P. | 13G/A | — | — | SEC |
| 7 | Feb 13, 2024 | Ubs Asset Management Americas Inc | 13G/A | — | — | SEC |
| 8 | Feb 12, 2024 | Flynn James E | 13G/A | 9.8% | 4.13M | SEC |
| 9 | Feb 12, 2024 | Vaddi Krishna | 13G/A | 11.1% | 4.91M | SEC |
| 10 | Jan 10, 2024 | Fmr LLC | 13G/A | 0.6% | — | SEC |
17 more beneficial-ownership filings on Premium
See the full Schedule 13D/13G history for Prelude Therapeutics Inc.
Unlock full historyTop Institutional Holders (13F)
Largest reported positions · latest quarter
| # | Fund | Shares | Value |
|---|---|---|---|
| 1 | Orbimed Advisors LLC | 10.91M | $37.31M |
| 2 | Baker Bros. Advisors LP | 10.12M | $34.62M |
| 3 | Kynam Capital Management, LP | 1.59M | $5.45M |
| 4 | Ecor1 Capital, LLC | 947.0K | $3.24M |
| 5 | Two Sigma Investments, LP | 923.6K | $3.16M |
| 6 | Sphera Funds Management Ltd. | 558.3K | $1.91M |
| 7 | Millennium Management LLC | 382.7K | $1.31M |
| 8 | Marshall Wace, LLP | 358.9K | $1.23M |
| 9 | Morgan Stanley | 322.2K | $1.10M |
| 10 | Blackrock, Inc. | 321.9K | $1.10M |