Institutional Ownership
Karyopharm Therapeutics Inc
CUSIP 48576U205COM NEWKPTIQ1 2026
13D / 13G Filings
12
Schedule 13D/13G on record
Beneficial Filers
10
Distinct reporting persons
Largest Stake
13.8%
Max % of class reported
Institutional Holders
73
13F filers (latest quarter)
Beneficial Owners — Schedule 13D / 13G
12 filings · latest Feb 17, 2026
| # | Filed | Reporting Person | Form | % of Class | Shares | Filing |
|---|---|---|---|---|---|---|
| 1 | Feb 17, 2026 | T. Rowe Price Investment Management, Inc. | 13G/A | 11.8% | 2.24M | SEC |
| 2 | Feb 12, 2026 | Adage Capital Management, L.P. | 13G/A | 2.4% | 436.7K | SEC |
| 3 | Feb 10, 2026 | Integrated Core Strategies (Us) LLC | 13G | 11.0% | 1.01M | SEC |
| 4 | Jan 29, 2026 | Affinity Asset Advisors, LLC | 13G/A | 8.6% | 1.71M | SEC |
| 5 | Nov 14, 2025 | Highbridge Capital Management, LLC | 13G/A | 4.9% | 650.0K | SEC |
| 6 | Nov 7, 2025 | T. Rowe Price Investment Management, Inc. | 13G/A | 13.8% | 2.30M | SEC |
| 7 | Nov 3, 2025 | J. Wood Capital Advisors LLC | 13G/A | 5.0% | 1.00M | SEC |
| 8 | Oct 30, 2025 | The Vanguard Group | 13G/A | 4.7% | 408.2K | SEC |
| 9 | Oct 17, 2025 | Opaleye Management Inc. | 13G | 9.5% | 1.57M | SEC |
| 10 | Aug 14, 2025 | T. Rowe Price Investment Management, Inc. | 13G | 8.4% | 728.8K | SEC |
2 more beneficial-ownership filings on Premium
See the full Schedule 13D/13G history for Karyopharm Therapeutics Inc.
Unlock full historyTop Institutional Holders (13F)
Largest reported positions · latest quarter
| # | Fund | Shares | Value |
|---|---|---|---|
| 1 | Commodore Capital LP | 1.95M | $10.86M |
| 2 | Ra Capital Management, L.P. | 1.92M | $10.68M |
| 3 | Adage Capital Partners Gp, L.L.C. | 1.81M | $10.06M |
| 4 | Goldman Sachs Group Inc | 947.6K | $5.28M |
| 5 | Catalio Capital Management, LP | 897.7K | $5.00M |
| 6 | Ikarian Capital, LLC | 733.4K | $4.09M |
| 7 | Affinity Asset Advisors, LLC | 500.0K | $2.79M |
| 8 | Avidity Partners Management LP | 463.7K | $2.58M |
| 9 | Soleus Capital Management, L.P. | 440.0K | $2.45M |
| 10 | Millennium Management LLC | 420.6K | $2.34M |