Institutional Ownership
Amylyx Pharmaceuticals Inc
CUSIP 03237H101COMAMLXQ1 2026
13D / 13G Filings
46
Schedule 13D/13G on record
Beneficial Filers
17
Distinct reporting persons
Largest Stake
18.9%
Max % of class reported
Institutional Holders
165
13F filers (latest quarter)
Beneficial Owners — Schedule 13D / 13G
46 filings · latest Feb 17, 2026
| # | Filed | Reporting Person | Form | % of Class | Shares | Filing |
|---|---|---|---|---|---|---|
| 1 | Feb 17, 2026 | Tcg Crossover Gp II, LLC | 13G/A | 11.0% | 6.24M | SEC |
| 2 | Feb 12, 2026 | Adage Capital Management, L.P. | 13G/A | 2.5% | 2.78M | SEC |
| 3 | Feb 5, 2026 | Fmr LLC | 13G/A | 15.0% | 16.47M | SEC |
| 4 | Jan 30, 2026 | The Vanguard Group | 13G | 5.3% | 5.80M | SEC |
| 5 | Jan 21, 2026 | Blackrock, Inc. | 13G/A | 7.1% | 7.78M | SEC |
| 6 | Nov 17, 2025 | Commodore Capital LP | 13G | 11.0% | 5.65M | SEC |
| 7 | Nov 14, 2025 | Perceptive Advisors LLC | 13G/A | 8.2% | 8.95M | SEC |
| 8 | Nov 14, 2025 | Point72 Asset Management, L.P. | 13G/A | 2.6% | 2.80M | SEC |
| 9 | Nov 13, 2025 | Adage Capital Management, L.P. | 13G/A | 6.4% | 6.82M | SEC |
| 10 | Oct 30, 2025 | The Vanguard Group | 13G/A | 4.9% | 5.27M | SEC |
36 more beneficial-ownership filings on Premium
See the full Schedule 13D/13G history for Amylyx Pharmaceuticals Inc.
Unlock full historyTop Institutional Holders (13F)
Largest reported positions · latest quarter
| # | Fund | Shares | Value |
|---|---|---|---|
| 1 | Fmr LLC | 16.63M | $231.16M |
| 2 | Blackrock, Inc. | 8.83M | $122.72M |
| 3 | Perceptive Advisors LLC | 8.28M | $115.16M |
| 4 | Tcg Crossover Management, LLC | 6.24M | $86.79M |
| 5 | Commodore Capital LP | 5.65M | $78.53M |
| 6 | Janus Henderson Group PLC | 4.99M | $69.26M |
| 7 | Saturn V Capital Management LP | 4.35M | $60.46M |
| 8 | Adage Capital Partners Gp, L.L.C. | 3.56M | $49.49M |
| 9 | First Light Asset Management, LLC | 3.19M | $44.35M |
| 10 | Driehaus Capital Management LLC | 2.99M | $41.52M |