Institutional Fund
Opaleye Management Inc.
Boston, MACIK 15958557 filings on record
Portfolio Value
$759.22M
Q1 2026
Holdings
54
Reported positions
New Buys
10
Opened this quarter
QoQ Change
+0.2%
from $757.89M
Portfolio Value Trend
Reported 13F value by quarter
Portfolio value trend — upgrade to see history
UpgradeTop Allocations
Largest positions by weight
- Harrow Inc13.2%
- Liquidia Corporation11.7%
- Eton Pharmaceuticals Inc9.3%
- Sol Gel Technologies5.2%
- Rhythm Pharmaceuticals Inc4.7%
- Apogee Therapeutics Inc4.3%
- Other51.7%
Portfolio Holdings
54 positions · Q1 2026
| # | Security | Shares | Value | % Port. | Δ Shares | Activity |
|---|---|---|---|---|---|---|
| 1 | Harrow Inc | 2.83M | $99.86M | 13.2% | −1.07M | Reduced |
| 2 | Liquidia Corporation | 2.54M | $88.82M | 11.7% | +110.0K | Added |
| 3 | Eton Pharmaceuticals Inc | 2.86M | $70.58M | 9.3% | 0 | Held |
| 4 | Sol Gel Technologies | 500.0K | $39.61M | 5.2% | +46.3K | Added |
| 5 | Rhythm Pharmaceuticals Inc | 123.0K | $35.32M | 4.7% | −207.0K | Reduced |
| 6 | Apogee Therapeutics Inc | 390.0K | $32.83M | 4.3% | +1.7K | Added |
| 7 | Disc Medicine Inc | 421.0K | $26.92M | 3.5% | +221.0K | Added |
| 8 | Urogen Pharma Ltd | 1.43M | $25.71M | 3.4% | +1.16M | Added |
| 9 | Crescent Biopharma Inc. | 1.31M | $24.11M | 3.2% | +134.3K | Added |
| 10 | Stoke Therapeutics Inc | 700.0K | $22.79M | 3.0% | +5.0K | Added |
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